CRISPR Seminar Basel

LubioScience  was established in 2004 and is located in Zurich, Switzerland. We are the distribution partner for some of the world's most recognized Life Science suppliers. With more than 12 years of experience in marketing & sales of Life Science reagents in Switzerland and Europe, we have a loyal customer base and an excellent relationship with our suppliers and brands. With our experienced and motivated team we aim to provide an efficient, reliable and professional service to our clients.

LubioScience/ IDT- Integrated DNA Technologies

Zentrum für Lehre und Forschung

Optimizing CRISPR ribonucleoproteins to achieve potent, precise genome editingSpeaker: Lai Chan, Field Application Manager - Functional Genomics Integrated DNA Technologies (IDT)Host: Hendrik Mallin, Key Account Manager, LubioScience GmbHAbstractWe will review how IDT developed the most potent set of genome editing tools on the market by combining the precision of chemically synthesized guide RNAs with high performance Cas9 and Cas12a (Cpf1) proteins. The Alt-R CRISPR system offers powerful on-target editing and reduced off-target effects compared to traditional approaches. This system is non-toxic and easy to deliver into a wide array of cells by lipofection or electroporation. We will present a novel high-fidelity Cas9 mutant that has been optimized to further reduce off-target gene editing while maintaining on-target potency. In addition, we will discuss a novel Cas12a(Cpf1) mutant with dramatically improved cleavage activity that rivals Cas9 and has improved low temperature cleavage activity making it a universal Cas12a (Cpf1) solution for genome editing in both animal and plant species. This presentation will review applications, including gene disruption and homology-directed repair (HDR) using both Cas9 and Cas12a systems.Following the seminar, Pizza and Drinks will be served outside the seminar room. We therefore kindly ask you to register for this event.

CRISPR Seminar Basel

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CRISPR Seminar Basel

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